Garry Hartley hammered a perfect hat-trick in Saxton Rovers' 7-0 thrashing of Dorchester United in Division 1.
Hartley's treble was made up of strikes with both feet and a header.
Steve Pitson, Mickey Beal, Ryan Johnson and Jim Smith completed the rout.
Kidlington Royals swept to a 5-0 win at Sandman. Mark White notched a double, with Gareth Davies, Tom Franklin and Craig Turnbull also netting.
Steve Doman hit a four-timer in ten-man Childrey OHB's 5-2 win against Standlake Garage.
Alan Haines also netted for Childrey, who had a man sent off in the first half.
Richard Bailey and Chris Bennell were on target for Garage.
In the only Division 2 game, OUP Wanderers racked up a thrilling 6-4 win over ten-man AFC Cowley.
Paul McNulty and Lee Kilpin hit doubles for the leaders, with Andy White and Richard Wells also on target.
Cowley's goals came from debutants Charlie Boss (2) and Simon Jones, and Dominic Bruno.
Craig Mays cracked a four-timer as Division 3A leaders Robin Hood won 5-1 at The Leys. Dean Mays also netted for Hood, with Jamie Tatam replying.
Abingdon Knights' excellent recent run came to end with a Fama Mara strike giving OARFDC a 1-0 victory.
Wayne Cox smashed a four-timer as Iffley Harriers thrashed basement boys Henry Box Old Boys 6-1.
Christos Antoniadis and Nathan East also netted for the Harriers, with Jon Rumbles replying.
Shelley Arms brushed aside The Railway Wheatley 4-1.
Chris Peck hit a double, with Dean Boyles and Guni Nuzi also netting.
Abba United ran out 4-1 winners at home to Dorchester Rebels.
Lee Clack grabbed a brace, with Scott Blackwell and Andy Sams also on target.
Steve Brazier's late strike earned Clanfield a point in a 2-2 draw at home to UYS United.
Ian Barrett also netted for Clanfield, with Andy Shellard and Lee Washington the UYS marksmen.
Brightwell Rebels beat Didcot Casuals 2-1 in a bad-tempered Division 3B top-of-the-table clash.
Strikes from Danny Weeks and Luke Higgins kept Rebels in top spot, with Jon Hedges netting for Casuals.
Dave Stebbings and Johnny James hit four-timers as The Bell Grove moved into second spot with a 9-0 annihilation of Sandman Res. Dan Gibbard was the other Grove scorer.
JET's Nigel King was a hat-trick hero in a 6-5 win against Bowyers Arms.
Tim Jones, Dan Forster and Dave Fernando also scored for JET, with Kearan Russell (3), Ollie Kearney and an own goal making up Bowyers' total.
Wallingford Wanderers edged out Sutton Symphony, with Ben Strudley and Pete Ashman on target.
Patrick Clark and Mark Druce netted in White Horse Abingdon's 2-1 win at Hampstead Norreys.
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