Witney & District FA: A rare strike from Pete Jenkins saw Spartan Rangers get off the mark with a 2-0 victory at previously unbeaten Millpark in the Premier Division.
Gavin Kominek opened their account before Jenkins sealed victory.
Ricky King bagged a brace as Brize Norton saw off neighbours Carterton 6-3.
Chris Cope, Dan Frizzell, Chris Days and Chris Marshall got the others, Dan Warner (2) and Will Griffiths replying.
Reigning champions Freeland were held to a 1-1 draw by neighbours Hanborough.
Freeland debutant Jefferson Harriott was on target, cancelling out a Paul Rose strike.
A double from Harry Hoyles helped North Leigh A to a 4-2 victory against West Witney.
Luke Simmons and Chris Thomas were also on target, with Matt Townsend replying with two penalties.
Supersubs Adam Rackham and Chris King bagged braces as Cassington edged an exciting Division 1 derby against Eynsham A 4-2.
An Ashley Blackwell double appeared to put Eynsham in control, before Rackham and King turned the game on its head.
Eynsham had Michael Riordan sent off for two bookings within two minutes.
Meanwhile, in the Fred Ford Cup, Mark Dorey netted a brace as Charlbury Town booked their place in round two with a 4-1 win over Division 3 outfit FC Chequers.
Martin Grimsley and Andy Woodley also scored, with Steve Foster netting for Chequers.
OTHER SCORERS
Prem Div: Aston 2 (B Sunblad, P Saunders), FC Nomads 1 (P Taylor), Hailey 1 (A Bridgeman), Ducklington 2 (S Coutts, C Palmer).
Div 1: Eynsham A 2, Cassington 4; Witney Royals 2 (R Plumb, L Edwards), Witney Wanderers 2 (C Bennell 2); Hanborough Res 6 (C Walker 3, J Mooney 2, R Hughes), North Leigh B 3 (J Buxton, W Frost, A Silence); West Witney Res 0, Bampton Tn 8 (S Godfrey 4, C Williams 3, T Buckingham); Ducklington Res 3 (D O'Sullivan 2, D Walker), FC Mills 2 (S West, A Moriarty).
Div 2: Kingham AB 2 (M Harding), Chippy Swifts 5 (W Tompkins 2, M Smith, R French, R Green); Combe 6, Freeland Res 1; Brize Norton Res 2 (M Jewell 2), Carterton A 1 (C Smith); Tackley 4 (C Betreen 2, R Moss, O Triggs), Wootton Spts 5 (R Brazier 4, G Clarke); Spartan Rgrs Res 6 (D Hall 3, C Baker 2, C Halkett), Wychwood Forest 0.
Div 3: Bampton Tn Res 3, Aston Res 0; Spartan Rgrs A 0, Ducklington A 4 (M Hawkins, I Lewis, R Kelly, T Merchant); Wychwood Forest Res 0, Witney Royals Res 4 (M Piper 2, S Ring, A Tyrell); Two Rivers 2 (J Tillson, J Hearn), Hanborough A 5 (A Hobley, T Hall, A Leach, L Busby, og); Southrop 5 (S Williams 2, C Indge, M Read, S Imms), FC Mills Res 1 (S Carcey).
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