Skipper Murray Nicholls was sent off as Old Woodstock Town’s superb run was ended by Bethnal Green in Saturday’s FA Carlsberg Vase fourth-round tie played at North Leigh.
Nicholls received his red card in the 26th minute following a foul.
But the Uhlsport Hellenic League hosts held out until half-time, without posing any real threat on the Bethnal Green goal.
The visitors, from the Essex Senior League, began to get on top in the second half and took the lead through a header from Aaron Stephenson on the hour mark.
Paul Burnett added a second eight minutes later, and Bethnal held out comfortably to reach the last 16.
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