Clanfield aim to reach the third round when they entertain high-flying Wessex League outfit Bemerton Heath Harlequins on Saturday.
Harlequins are second in their league and have a sound record in the competition.
Clanfield have beaten Warminster Town and Fairford Town in the previous rounds.
Joint manager Pete Osborne adds Kevin Lewis and Ben Acock to the squad. Karl Dickenson is out.
Wantage Town welcome back Tom Austin from injury when they host Premier Division rivals Binfield.
Richie Guy returns after a loan spell at Hungerford.
Witney United face a tricky trip to Combined Counties League side Colliers Wood United.
Witney were thumped 4-1 by fellow strugglers Carterton in midweek, and will be without cup-tied striker Joe Tustain.
Former AFC Totton striker Lee Stevens will lead the attack with Sean McKeon.
Jon Rixon and Carl Evans return, but Vinny Byfield and James Lambert are unavailable.
Lewis Colwell (groin) is a doubt.
TOMORROW’S VASE LINE-UPS Clanfield (v Bemerton Heath, home): from Brain, Dixon, Oswin, Butt, Blakeley, Odom, Bishop, S Olphert, C Mays, D Mays, Lewis, Miller, Little, Rodgers, Bush, Cheetham, Acock.
Wantage Tn (v Binfield, home): from Tucker, Rowe, Webb, Wallbridge, Biddle, Malton, Jones, Bruce, Claydon, McCullough, Butler, Dewar, Belcher, Guy, Langford, Austin, Cattell, Edney, Belcher, Keen.
Witney Utd (v Colliers Wood Utd, away): from Whylly, Tassell, T Smith, Nagy, Evans, Steedman, Colwell, Rixon, McNally, Jack Smith, Jason Smith, Blenford, McKeon, Stevens, Everett, Wright, Allmond, Harrison.
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