A Nick Acock brace helped Enstone to a 6-2 win at derby rivals Chadlington in the Oxfordshire Senior League Premier Division.
Robert Busby and Acock's first gave Enstone a two-goal cushion.
Although Sean Gilbert reduced the arrears, a James Watkins brace restored Enstone's advantage, before a Busby own-goal cut the deficit.
After the break, Acock completed his brace, before a late double from James Watkins compounded Chadlington's misery.
Adderbury Park eased to a 2-0 win against Kennington, thanks to a Gary Crook penalty and a Neil Skidmore strike.
Rover Cowley were held to a goalless draw at home by Marston Saints.
The closest either side came to scoring was when Kane Adams's shot hit the Rover bar.
Garsington keeper Chris Flowers saved a penalty as they beat Eynsham 1-0.
Tyrone Brackett fired Garsington ahead, before Flowers performed his heroics four minutes from time.
A double from Paul Cooper earned Horspath a 2-0 win at Oxford University Press.
A hat-trick from Todd Parker-Hunt was in vain for ten-man Bletchingdon as they lost 4-3 defeat at home to Stonesfield.
James Clarke gave Bletchingdon the lead from 30 yards, before Parker-Hunt levelled with a penalty.
A Paul Knight penalty and a Dan Sherbourne strike gave Stonesfield a 3-1 advantage.
Parker-Hunt reduced the arrears with his second spot-kick.
After the break, Steven Gray saw red, before Nick Higgs extended Stonesfield's advantage.
Parker-Hunt completed his hat-trick.
A late double from sub Craig Duckett, including a penalty, salvaged a 2-2 draw for Middleton Cheney against ten-man Yarnton in Division 1.
Yarnton led through Ryan Baxter-Richards, before keeper Paul Brandish saved Tristan Salt's penalty.
Yarnton had James Bowerman sent off for a two-footed foul on Middleton’s Neil Wright.
Paul Skinner doubled Yarnton's lead before Duckett took over.
A Jamie Clack brace helped Charlton beat Kidlington 5-0.
Matt Hillsdon, Chris Staker and Chris Hancock were also on target.
A Rocky Whiting double and strikes from Thomas Gaughan and Jason McGill earned Garsington Res a 4-0 victory against Oakley.
BCS Bardwell beat Watlington 3-2.
Darren Huckin cancelled out Cori Saunders' opener for Watlington.
However, substitute Peter Allison restored Bardwell's advantage.
Dave King equalised, but Huckin slammed home the winner.
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