Launton Sports have sacked manager Robert Dick after a poor run of results.
They are bottom of FTL Futbol Hellenic League Division 1 East.
On Saturday, they face Wokingham & Emmbrook.
Bicester Town are without defender Ben Elkington for their Premier Division clash with Witney United due to a serious knee injury.
They are also without Ian Lovegrove (ankle surgery) and Sam Houlihan (away), while John Umney (groin) is a doubt.
Jefferson Harriott is due to make his debut after signing from Abingdon Town.
Nathan Woodley could make his bow for Witney after he joined Southern League side Abingdon United.
SATURDAY'S SQUADS Launton Sp (v Wokingham & Emm, home): from Clifford, Anderson, G Bedford, Blossom, Crognale, Jenkins, Jeskins, C Jones, J Lisseter, P Lisseter, Moore, Neale, Ross, D Smith, Wright.
Bicester Tn (v Witney Utd, home): from McNamara, Skowronski, Hunt, French, Lambourne, Ames, Leggett, Johnson, Butler, Kyberd, Williams, Emsden, Harriott, Spittle, Umney.
Witney Utd (v Bicester Tn, away): from Beames, Smith, Moss, Steedman, Byfield, Peirson,Wallbridge, Henderson, Woodley, JP Mills, Jamie Mills, Lewis, Burnley, Younie, McMahon, Griffin, Thompson.
Headington Ams (v Cirencester Utd, home): from G Simmonds, Brown, Parsons, Pearce, Hafiz, M Johnson, N Johnson, Drewett, A Simmonds, Jacobs, B Cuff, Hill, Phillips, L Cuff, Woodward.
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