Oxford University opened their campaign with a 53-7 victory over Henley Alliance at Dry Leas.
The Dark Blues led 19-0 at the break and pulled away after that.
Lock Ian Kench and flanker Dave Fenlon scored two tries apiece with centre Sam Humphry-Baker, wings Will Browne and Tim Catling, flanker Ross Biestman and fly half Stuart O'Flanagan also crossing the line.
O'Flanagan added a conversion, while full-back Ross Swanson kicked three.
Henley's only try was scored by Oxford Blue Euan Sadden, who was loaned to the home side for the day!
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