Burglars ripped open two doors at Bicester Town Football Club before stealing cash and alcohol in the eleventh attack on the club in three years.
Club chairman David Simpson said he was gutted by the attack, which he believes caused more than £3,000 damage.
He said: "They ripped through two doors, took the skin off an alarmed door and then ripped out the alarm system and broke glass."
Mr Simpson added the thieves had completely trashed the clubhouse before fleeing with six bottles of spirits, cases of bottled beer, change from a pay phone and an empty cashier's till.
The till was found in a nearby churchyard and the bottles were also found and are now being examined for evidence.
Over the past few years attacks have cost the club thousands of pounds in new security measures and insurance premium hikes.
Mr Simpson said: "Just how much can this football club take? The club is in danger of becoming uninsurable.
"The way the alarm was disabled there was a definite intent to get more than they got. They seemed to want cash or something to sell which makes me think it is drug related."
The burglars forced their way into the club between 1pm and 8am on Easter Monday.
Bicester Rugby Club, which is next to the football club off Oxford Road, has also been the victim of two attempted break-ins in the past six weeks - the most recent one the weekend before Easter.
Pc Saif Jung, who is investigating the football club break-in, said: "The attack on the property was a concerted one because the doors are very sturdy and resistant to attack. It would have taken quite some time and effort to break in."
Last August thieves used a crowbar to prise off the cellar door at the football club and stole alcohol worth about £150. In July 2004, vandals caused £1,000 damage when they broke in, wrecking a door, a cash till and an alarm system. Over Christmas 2004, vandals caused £400 damage smashing windows.
Anyone with information on the attacks should call Bicester police on 08458 505505 or Crimestoppers on 0800 555111.
* On Sunday a charity football match between Swindon Town Veterans and Banbury and Jersey Veterans will be held at the club to raise money for the British Heart Foundation.
Mr Simpson said: "It's business as usual. These vandals won't beat us."
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