Changes in intellectual outlook during the 16th and 17th centuries formed the basis for the so-called 'scientific revolution' which brought together the humanities and natural sciences in an unprecedented ferment of conceptual and practical creativity. Jardine argues that those caught up in its excitement from Locke to Pepys, Newton to Wren were equally influenced and fascinated by the 'two cultures' of art and science. (Abacus, 15)