International City law firm Barlow Lyde & Gilbert has taken over Duncombe Commercial Solicitors, based on the Oxford Business Park.
Oxford-based partner Dr Janita Good said: "We are very excited to become part of the first City law firm to have a presence in Oxford.
"An Oxford office will give BLG a unique platform from which to serve clients in the technology, IT, biotech and e-business sectors."
In just four years BLG has developed one of the largest technology practices in Europe acting for major IT and consulting clients.
John Longdon, head of BLG's corporate team, said: "This acquisition emphasises BLG's commitment to technology and e-business related work and will enable us to take advantage of Oxford's reputation as a world centre for excellence.
"As a City firm in Oxford, BLG will be uniquely positioned to support the leading businesses in these fast-growing sectors."
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