Oxford City duo Steve Arkins and Paul Woodhouse are out of the home clash with Uxbridge on Saturday (Oct 27).
Arkins is suffering from shin splints, while Woodhouse has a pulled hamstring.
However, Mark Druce is expected to be fit for City, who have won four out of their last five home league games.
Manager Paul Lee said: "Uxbridge will be a tough game. They beat Yeading 6-1 on Tuesday, so we are expecting a hard match."
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