A number of trains have been cancelled between Oxford and London Marylebone this weekend, causing severe disruption.

Chiltern Railways has warned there will be fewer trains running from today (October 26) until Monday (October 28).

The train operator also warned that there 'may be short notice cancellations'. 

A statement from Chiltern Railways said: "We will be operating fewer trains between London Marylebone and Oxford.

READ MORE: Lane remains closed on A34 southbound for emergency works

"Please check before you travel as there may be short notice cancellations."

Today, the 4.07pm train from London Marylebone to Oxford, due to arrive at 5.35pm, has been cancelled.

READ MORE: M40 crash leads to man being left with broken jaw in assault

The 5.45pm train from Oxford to London Marylebone today, due to arrive at 7.15pm has also been cancelled. 

When asked on social media why the disruption is in place, a spokesperson for Chiltern Railways said it is due to 'operational challenges'.

The line between Beaconsfield and London is also blocked due to a passenger being taken ill on a train, causing delays of up to 40 minutes.