New yellow weather warnings for rain have been issued for Oxfordshire ahead of Storm Ciaran moving in on Wednesday night.
The Met Office issued a yellow weather warning with a heavy rain forecast likely to cause disruption to travel and flooding.
The heavy rain warning will be in place on Wednesday, November 1 from 6pm until midnight on Thursday, November 2.
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The forecast warned that homes and businesses could be flooded and said some communities may be cut off by flooded roads
It added that fast-flowing or deep floodwater is possible which could cause a danger to life.
The weather warning also says to expect delays or cancellations to train and bus services.
A Met Office spokesman said: "Periods of heavy rain, associated with Storm Ciarán, are expected to affect much of southern and western England and Wales from Wednesday evening and throughout Thursday.
"Over southern England rain may be accompanied by occasional rumbles of thunder in a few places.
"A further 20-30 mm is likely quite widely, but 40-60 mm may accumulate in a number of places, especially, but not exclusively, over higher ground.
"Upland areas of southwest England and Wales may see 80 mm of rain in a few locations with the potential for in excess of 100 mm in a few locations across north Wales.
"Given this amount of rainfall, the current saturated conditions, and the potential for fallen leaves to block drains etc, further impacts are likely."
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As well as rain warnings, the Met Office has issued yellow wind warnings for much of the south coast of England during the same period reaching as far up as Henley in South Oxfordshire.
Met Office deputy chief meteorologist Dan Suri said a cold front would bring bursts of heavy rain and coastal gusts of 60 to 70mph along the south coast.
He said: “Wind and rain warnings associated with Storm Ciaran are in force from Wednesday night onwards into Friday.
“As well as strong winds, this deep low pressure system will bring heavy rain to many parts of the UK.
“Much of southern England and south Wales, as well as parts of north Wales, northeast England, southeast Scotland and perhaps the east of Northern Ireland look to see the wettest conditions between Wednesday evening and Friday morning.”
The Environment Agency had issued 24 flood warnings for England by 3am on Wednesday morning with 108 flood alerts.
Kate Marks, flood duty manager at the Environment Agency said “significant flooding” is possible.
She said: “We advise people to stay away from swollen rivers and urge people not to drive through flood water as just 30cm of flowing water is enough to move your car.
”The weather is not showing much sign of a rapid improvement once Storm Ciaran does pass.
Met Office deputy chief meteorologist Steven Keates said: “Once Storm Ciaran has passed, the weather over the weekend continues to look unsettled for many with more showers and rain at times.
“Warnings will continue to be updated over the coming days, so it is important to stay up to date with the Met Office forecast and warnings in your area.”
You can see the full weather forecast via the Met Office website.
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