A Buckinghamshire woman whose red Peugeot 106 left the road and hit trees on a central reservation on Monday afternoon remains in a serious condition in Oxford's John Radcliffe Hospital.
The road between Marsh Lane and the Cutteslowe roundabout, Oxford, was shut for more than three hours following the crash.
Police are appealing for witnesses to the collision to come forward.
Anyone with any information is asked to contact Pc Martin Mann on 08458 505505.
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