Seamer Ollie Murrey took 7-15 as Banbury 2nd humiliated local rivals Banbury Twenty by bowling them out for 49 in Division 1.
Murrey was backed up at the other end by Ross Freeman, who finished with figures of 3-26 in bowler-friendly conditions.
The visitors then wrapped up a seven-wicket victory.
Banbury Twenty 3pts, Banbury 2nd 25
Great & Little Tew's fragile batting line up was exposed when they were bowled out for 110 at Bicester & North Oxford.
Only Kevin Taylor (32) made much progress as Stephen West, Matthew Woods and Paul Jeacock each took three wickets.
Earlier Bicester had posted 218-7 after being inserted, with key contributions coming from Andrew House (65) and Duncan Bradshaw (58).
Bicester & North Oxford 25, Great & Little Tew 4
Aston Rowant overcame Oxford Downs and the weather to make it two wins out of two.
Put into bat, Downs made 200-7 from their 52 overs, with Frankie Crouch (52) providing the backbone before a breezy 51 from Jamie Perkin took the visitors to a competitive total.
Alex Jewell (71) and Wes Morrick (63) had Rowant in command, but the loss of five overs to a rain delay and some tidy bowling by Marc Milligan (3-51) and Richard West (3-53) put it back in the balance.
Rowant skipper Simon Bird finally scrambled the winning runs with one over to spare, but his side were then docked two points for their slow over rate.
Aston Rowant 23, Oxford Downs 10
The needle match between Oxford 2nd and Horspath - clubs that merged and 'de-merged' in recent years - petered out into a draw after time was lost to the weather.
Chris Penner hit 105 from 143 balls and Joey Todd 45 from 74 deliveries in Horspath's 227-8.
Joe Endicott took 4-54 and then 31 runs for Oxford, who had reached 106-5 from 30 overs when time ran out.
Oxford 2nd 7, Horspath 12
Paul Hemming made the most of some lacklustre Cumnor fielding to hit 55 and lay the platform for Shipton-under-Wychwood's 217-7.
Sahan Wijneratne hit a stylish 69 before Jon Hartley (33) struck some characteristically lusty blows to finish off the innings.
Steve Slade took 4-66 for the hosts, who were well placed while Graham Scott (33) and Andrew Robertson (37) were together.
But left arm spinner Shaun Miller (5-95) engineered a middle-order collapse and despite some impressive hitting by No 11 Ayaz Khan (47), Cumnor were dismissed for 184.
Cumnor 6, Shipton-under-Wychwood 25
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