Robert Green and Josh Cox struck gold for the St Birinus School Club, Didcot, at the British Schools' Weightlifting Championships in Birmingham.
Green triumphed in the under 16 56kg class at Oldbury Sports College, while Cox took the honours in the under 14 45kg category.
They spearheaded an eight-medal haul by the St Birinus boys.
Eddie Chambers won silver in the under 16 50kg class, with Louis Baker taking bronze.
Adam Lane claimed silver in the under 16 59kg section, and there were also silvers at under 13 for James Byewater at 45kg and Lewis Miltenburger at 62kg.
Danny Slater won bronze in the under 16 62kg class, and Reece Ward just missed out on a medal, finishing fourth in the under 14 62kg section.
Cox and Chambers now go on to compete in the British Junior Championships in Halifax on Saturday, March 29.
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