An Ocado food delivery van was involved in a collision this morning, causing delays on the A420.
Fire crews are warning drivers to approach the area with caution.
The incident happened between Kingston Bagpuize and Fyfield near Abingdon.
Oxfordshire Fire and Rescue service has said Red Watch from Abingdon Fire Station attended the scene to keep the area safe and contain fuel spills.
The fire service has also warned that traffic may be heavier than usual.
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